ChemicalBook--->CAS DataBase List--->66309-69-1

66309-69-1

66309-69-1 Structure

66309-69-1 Structure
IdentificationMore
[Name]

Cefotiam hydrochloride
[CAS]

66309-69-1
[Synonyms]

(6r-trans)-7-[2-(2-aminothiazol-4-yl)acetamido]-3-[[[1-[2-(dimethylamino)ethyl]-1h-tetrazol-5-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
CEFOTIAM
CEFOTIAM 2HCL
cefotiam hydrochloride
cefotiamdihydrochloride
dihydrochloride,(6r-trans)--oxo
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, dihydrochloride, (6R,7R)-
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, dihydrochloride, (6R-trans)-
Abbott 48999
Halospor
Pansporin
Pansporine
Spizef
Sporidyn
(6R-trans)-7-[2-(2-aminothiazol-4-yl)acetamido]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
Cefapicol
Kemisporin
Sepidnarin
[EINECS(EC#)]

266-312-6
[Molecular Formula]

C18H23N9O4S3
[MDL Number]

MFCD00865087
[Molecular Weight]

525.63
[MOL File]

66309-69-1.mol
Chemical PropertiesBack Directory
[Melting point ]

>93°C (dec.)
[Boiling point ]

94℃
[RTECS ]

XI0367000
[Fp ]

>110°(230°F)
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

H2O: ≥22M
[form ]

powder
[color ]

white to tan
[Water Solubility ]

Soluble in water
[Stability:]

Hygroscopic
[InChIKey]

BWRRTAXZCKVRON-DGPOFWGLSA-N
[CAS DataBase Reference]

66309-69-1(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36
[Safety Statements ]

26
[WGK Germany ]

3
[HS Code ]

2941906000
Hazard InformationBack Directory
[Uses]

A broad spectrum antibiotic
[Uses]

antiprotozoal, trypanocidal, antiviral
[Uses]

Cephalosporin Antibiotic.
[Definition]

ChEBI: The dihydrochloride salt of cefotiam.
[Brand name]

Ceradon (Takeda).
[Pharmacokinetics]

Cefotiam Hydrochloride is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
Spectrum DetailBack Directory
[Spectrum Detail]

Cefotiam hydrochloride(66309-69-1)1HNMR
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